Epsom salts is Magnesium sulfate and is used at a rate of 1/4 to 1 teaspoon per gallon of water to provide suplemental Mg (once a month or a couple times a year).
If your tapwater has some dissolved Calcium and Magnesium carbonates you probably are supplying enough, or if you are using a Cal-Mag type fert.
Some folks using RO water or rain water add a little (1/8 teaspoon) of Calcium Nitrate and Magnesium Sulfate on alternate waterings. Don't mix the two together in high concentration, the Ca ions will combine with the sulfate to form gypsum which will precipitate out.