I don't need to worry about it since moving to the greenhouse, BUT, when I grew in the window I had trays and saucers of water on the shelves and a humidistat to monitor things and did notice a 10 point or more rise. Grouping plants also helped as well.
Physics tells us that if there is no air movement, evaporating water molecules will "sink" so putting the trays on a high shelf should be beneficial ( theory only).
Let us know if you notice an improvement with the mister, lots of growers swear by them I've read.